NVEM0 is implemented in the main FLASH memory of the SPLat processor. Please refer to the documentation for each specific controller product for details of speed and endurance.
It is important to take into account the speed of the NVEM0 if your program is performing very fast, critical operations. In most cases the NVEM0 will be fast to read but slow to write. While it is being written the processor will be unable to do anything else, so effectively your controller will be asleep for that time.
Endurance is the memory's ability to withstand repeated writes. FLASH memory has a finite life. Once it has performed a certain number of write cycles it becomes worn and is likely to return corrupted data. Reading the data has no effect on life.
At time of writing all foreseeable implementations of NVEM0 will be severely limited in endurance, and will basically be suitable only for very occasional writing (maybe a few hundred times). Check the product-specific documentation carefully!